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Article

GIMAP GTPase family genes: potential modifiers in autoimmune diabetes, asthma, and allergy.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2015

Heinonen Mirkka T, Laine Antti-Pekka, Söderhäll Cilla, Gruzieva Olena, Rautio Sini, Melén Erik, Pershagen Göran, Lähdesmäki Harri J, Knip Mikael, Ilonen Jorma, Henttinen Tiina A, Kere Juha, Lahesmaa Riitta

Abstract excerpt

GTPase of the immunity-associated protein (GIMAP) family members are differentially regulated during human Th cell differentiation and have been previously connected to immune-mediated disorders in animal studies. GIMAP4 is believed to contribute to the Th cell subtype-driven immunological balanc...

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Identifiers

PMID: 25964488
DOI: 10.4049/jimmunol.1500016
PMCID: PMC4456634

Genes

GIMAP4
GIMAP5
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25964488-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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