Article
The role of melanocortin 3 receptor gene in childhood obesity.
Diabetes - 1 Oct 2007
Lee Yung Seng, Poh Larry Kok Seng, Kek Betty Lay Kee, Loke Kah Yin
Abstract excerpt
OBJECTIVE: Melanocortin 3 receptor (MC3R) plays a critical role in weight regulation of rodents, but its role in humans remains unclear. The objective of this study was to identify genetic variants of the MC3R gene and determine its association with childhood obesity. RESEARCH DESIGN AND METHODS: We screened 201 obese children for MC3R gene mutations with anthropometric measurements, blood tests, feeding...
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