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Article

Effect of the melanocortin-3 receptor C17A and G241A variants on weight loss in childhood obesity.

The American journal of clinical nutrition - 1 Apr 2007

Santoro Nicola, Perrone Laura, Cirillo Grazia, Raimondo Paolo, Amato Alessandra, Brienza Carmine, Del Giudice Emanuele Miraglia

Abstract excerpt

BACKGROUND: The central melanocortin system is critical for the long-term regulation of energy homeostasis. Melanocortin-3 receptor (MC3R) knock-out mice, despite being hypophagic, have increased fat mass and higher feed efficiency than do their wild-type littermates. OBJECTIVE: The aim was to evaluate whether, in childhood obesity, MC3R variants are associated with changes in fatness reduction as a consequence...

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Source

Identifiers

PMID: 17413091
DOI: 10.1093/ajcn/85.4.950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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