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Article

Novel melanocortin 4 receptor gene mutations in severely obese children.

Clinical endocrinology - 1 Apr 2008

Lee Yung Seng, Poh Larry Kok Seng, Kek Betty Lay Kee, Loke Kah Yin

Abstract excerpt

OBJECTIVE: Melanocortin 4 receptor (MC4R) deficiency is the commonest monogenic form of obesity. The significance of MC4R mutations in Asian obese populations has not been adequately examined. The objective of this study was to determine the role of MC4R mutations in severely obese Asian children. DESIGN: We screened 227 obese local children and adolescents for MC4R gene mutations by polymerase chain reaction and...

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Source

Identifiers

PMID: 17941900
DOI: 10.1111/j.1365-2265.2007.03071.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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