Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel melanocortin 4 receptor gene mutations in severely obese children.

Clinical endocrinology - 1 Apr 2008

Lee Yung Seng, Poh Larry Kok Seng, Kek Betty Lay Kee, Loke Kah Yin

Abstract excerpt

OBJECTIVE: Melanocortin 4 receptor (MC4R) deficiency is the commonest monogenic form of obesity. The significance of MC4R mutations in Asian obese populations has not been adequately examined. The objective of this study was to determine the role of MC4R mutations in severely obese Asian children...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Child
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Obesity

Share to Receptor, Melanocortin, Type 4

Share to Severity of Illness Index

Share to Singapore

Source

Identifiers

PMID: 17941900
DOI: 10.1111/j.1365-2265.2007.03071.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17941900-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel melanocortin 4 receptor gene mutations in severely obese children.PMID 17941900Read ↗

Melanocortin 3 receptor gene and melanocortin 4 receptor gene mutations: the Asian Perspective.Semantic proximity Read ↗

A Novel Melanocortin 3 Receptor Gene (MC3R) Mutation Associated with Severe ObesitySemantic proximity Read ↗

A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity.Semantic proximity Read ↗

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating.Semantic proximity Read ↗

Clinical and functional relevance of melanocortin-4 receptor variants in obese German children.Semantic proximity Read ↗

Melanocortin-4 receptor gene mutations in a Dutch cohort of obese children.Semantic proximity Read ↗

A novel mutation Thr162Arg of the melanocortin 4 receptor gene in a Spanish children and adolescent population.Semantic proximity Read ↗

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene.Semantic proximity Read ↗

Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis.Semantic proximity Read ↗

Melanocortin 4 receptor (MC4R) gene variants in children and adolescents having familial early-onset obesity: genetic and clinical characteristics.Semantic proximity Read ↗

Homozygous null mutation of the melanocortin-4 receptor and severe early-onset obesity.Semantic proximity Read ↗

Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.