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Article

Sequence polymorphisms cause many false cis eQTLs.

PloS one - 18 Jul 2007

Alberts Rudi, Terpstra Peter, Li Yang, Breitling Rainer, Nap Jan-Peter, Jansen Ritsert C

Abstract excerpt

Many investigations have reported the successful mapping of quantitative trait loci (QTLs) for gene expression phenotypes (eQTLs). Local eQTLs, where expression phenotypes map to the genes themselves, are of especially great interest, because they are direct candidates for previously mapped physiological QTLs. Here we show that many mapped local eQTLs in genetical genomics experiments do not reflect actual...

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Identifiers

PMID: 17637838
DOI: 10.1371/journal.pone.0000622
PMCID: PMC1906859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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