Article
Validating discovered Cis-acting regulatory genetic variants: application of an allele specific expression approach to HapMap populations.
PloS one - 1 Jan 2008
Campino Susana, Forton Julian, Raj Srilakshmi, Mohr Bert, Auburn Sarah, Fry Andrew, Mangano Valentina D, Vandiedonck Claire, Richardson Anna, Rockett Kirk, Clark Taane G, Kwiatkowski Dominic P
Abstract excerpt
BACKGROUND: Localising regulatory variants that control gene expression is a challenge for genome research. Several studies have recently identified non-coding polymorphisms associated with inter-individual differences in gene expression. These approaches rely on the identification of signals of association against a background of variation due to other genetic and environmental factors. A complementary approach...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.