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Article

Single nucleotide polymorphisms affect both cis- and trans-eQTLs.

Genomics - 1 Jun 2009

Chen Lang, Page Grier P, Mehta Tapan, Feng Rui, Cui Xiangqin

Abstract excerpt

Single nucleotide polymorphisms (SNPs) between microarray probes and RNA targets can affect the performance of expression array by weakening the hybridization. In this paper, we examined the effect of the SNPs on Affymetrix GeneChip probe set summaries and the expression quantitative trait loci (eQTL) mapping results in two eQTL datasets, one from mouse and one from human. We showed that removing SNP-containing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19248827
DOI: 10.1016/j.ygeno.2009.01.011
PMCID: PMC4041081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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