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Article

Low affinity interaction of peptide-MHC complexes with T cell receptors.

Science (New York, N.Y.) - 20 Dec 1991

Matsui K, Boniface J J, Reay P A, Schild H, Fazekas de St Groth B, Davis M M

Abstract excerpt

The interaction of antigen-specific T cell receptors (TCRs) with their ligands, peptides bound to molecules of the major histocompatibility complex (MHC), is central to most immune responses, yet little is known about its chemical characteristics. The binding to T cells of a labeled monoclonal an...

Topics

Amino Acid Sequence
Animals
Antibodies, Monoclonal
Antigen-Presenting Cells
Cell Line
Genetic Variation
Immunoglobulin Fab Fragments
Kinetics
Macromolecular Substances
Major Histocompatibility Complex
Models, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Peptides

Protein Binding

Receptors, Antigen, T-Cell

T-Lymphocytes

Source

Identifiers

PMID: 1763329
DOI: 10.1126/science.1763329

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1763329-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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