Article
Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis.
Spine - 15 Jul 2007
Qiu Xu Sheng, Tang Nelson L S, Yeung Hiu Yan, Lee Kwong-Man, Hung Vivian W Y, Ng Bobby K W, Ma Suk Ling, Kwok Rachel H K, Qin Lin, Qiu Yong, Cheng Jack C Y
Abstract excerpt
STUDY DESIGN: A genetic association study to comprehensively investigate variations of melatonin receptor 1B gene polymorphism by a set of tagging single nucleotide polymorphisms (tagSNPs) derived from the International Hapmap project. OBJECTIVES: To determine whether melatonin receptor 1B (MTNR1B) gene polymorphisms are associated with the predisposition and/or disease severity of adolescent idiopathic scoliosis...
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