Article
Association study of tryptophan hydroxylase 1 and arylalkylamine N-acetyltransferase polymorphisms with adolescent idiopathic scoliosis in Han Chinese.
Spine - 15 Sept 2008
Wang Hai, Wu Zhihong, Zhuang Qianyu, Fei Qi, Zhang Jianguo, Liu Yong, Wang Yipeng, Ding Yaozhong, Qiu Guixing
Abstract excerpt
STUDY DESIGN: A genetic association study of tryptophan hydroxylase 1 gene (TPH1) and arylalkylamine N-acetyltransferase gene(AANAT) with adolescent idiopathic scoliosis (AIS) in Han Chinese. OBJECTIVE: To access whether TPH1 and AANAT polymorphisms are associated with the predisposition, gender, and/or severity of AIS. SUMMARY OF BACKGROUND DATA: Studies have shown that AIS is a multifactorial inheritance...
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