Article
The polymorphisms of melatonin receptor 1B gene (MTNR1B) (rs4753426 and rs10830963) and susceptibility to adolescent idiopathic scoliosis: a meta-analysis.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association - 1 Jul 2015
Yang Mingyuan, Wei Xianzhao, Yang Wu, Li Yanming, Ni Haijian, Zhao Yingchuan, Chen Ziqiang, Bai Yushu, Li Ming
Abstract excerpt
OBJECTIVE: To determine whether MTNR1B rs4753426 and rs10830963 polymorphisms are correlated with AIS. Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity, while its etiology remains uncertain. Melatonin receptor 1B (MTNR1B) gene polymorphisms have been found to be significantly associated with AIS risk; however, some of these results are controversial. METHODS: An systematic online...
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