Article
The role of melatonin receptor 1B gene (MTNR1B) in adolescent idiopathic scoliosis--a genetic association study.
Studies in health technology and informatics - 1 Jan 2006
Qiu X S, Tang N L, Yeung H Y, Qiu Y, Qin L, Lee K M, Cheng J C Y
Abstract excerpt
UNLABELLED: Many studies have demonstrated the role of melatonin in the etiology of AIS. Previous studies have shown that there is no evidence of mutations in the melatonin receptor 1A gene in AIS patients. In this study, we have examined the role of melatonin receptor 1B in predisposition for AIS. Using haplotype block tagging technique, a set of tagging SNPs were defined for MTNR1B from the Han Chinese data of...
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