Lack of association between adolescent idiopathic scoliosis and previously reported single nucleotide polymorphisms in MATN1, MTNR1B, TPH1, and IGF1 in a Japanese population.

doi:10.1002/jor.21347

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Article

Lack of association between adolescent idiopathic scoliosis and previously reported single nucleotide polymorphisms in MATN1, MTNR1B, TPH1, and IGF1 in a Japanese population.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jul 2011

Takahashi Yohei, Matsumoto Morio, Karasugi Tatsuki, Watanabe Kota, Chiba Kazuhiro, Kawakami Noriaki, Tsuji Taichi, Uno Koki, Suzuki Teppei, Ito Manabu, Sudo Hideki, Minami Shohei, Kotani Toshiaki, Kono Katsuki, Yanagida Haruhisa, Taneichi Hiroshi, Takahashi Atsushi, Toyama Yoshiaki, Ikegawa Shiro

Abstract excerpt

Adolescent idiopathic scoliosis (AIS) is a spinal deformity most commonly arising in apparently healthy girls around puberty. AIS has a strong genetic predisposition. Several genetic associations between AIS and single nucleotide polymorphisms (SNPs) have been reported; common SNPs in the genes for matrilin 1 (MATN1), melatonin receptor 1B (MTNR1B), tryptophan hydroxylase 1 (TPH1), and insulin-like growth factor...

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Identifiers

PMID: 21308753
DOI: 10.1002/jor.21347

Genes

IGF1
MATN1
TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Lack of association between adolescent idiopathic scoliosis and previously reported single nucleotide polymorphisms in MATN1, MTNR1B, TPH1, and IGF1 in a Japanese population.PMID 21308753Read ↗

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