Article
The relative influence of diet and serum concentrations of organochlorine compounds on K-ras mutations in exocrine pancreatic cancer.
Chemosphere - 1 Apr 2010
Gasull Magda, Porta Miquel, Pumarega José, Vioque Jesús, Bosch de Basea Magda, Puigdomènech Elisa, Morales Eva, Grimalt Joan O, Malats Núria
Abstract excerpt
BACKGROUND: In exocrine pancreatic cancer (EPC) mechanistic relationships may exist among some organochlorine compounds (OCs) and mutations in the K-ras oncogene, as well as among the latter and dietary factors. OBJECTIVE: To analyze (1) the relationship between food intake and serum concentrations of OCs in EPC patients and (2) the relative influence of food and OCs on the frequency of K-ras mutations in EPC....
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