Article
Past medical conditions and K-ras mutations in pancreatic ductal adenocarcinoma: a hypothesis-generating study.
Cancer causes & control : CCC - 1 Jul 2009
Crous-Bou Marta, Porta Miquel, Morales Eva, López Tomàs, Carrato Alfredo, Puigdomènech Elisa, Real Francisco X
Abstract excerpt
BACKGROUND: In pancreatic ductal adenocarcinoma (PDA) evidence on the etiopathogenic role of past medical conditions in the occurrence and persistence of K-ras mutations is scant. METHODS: Incident cases of PDA were interviewed face-to-face about past medical history and other factors. Logistic regression was used to compare PDA cases (n = 120) with wild-type and mutated K-ras tumors (case-case study). RESULTS:...
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