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Strategies to Modulate the Redifferentiation of Chondrocytes

22 Nov 2021

Abstract excerpt

Because of the low self-healing capacity of articular cartilage, cartilage injuries and degenerations triggered by various diseases are almost irreversible. Previous studies have suggested that human chondrocytes cultured in vitro tend to dedifferentiate during the cell-amplification phase and lose the physiological properties and functions of the cartilage itself, which is currently a critical limitation in the...

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PMID: 34881234
DOI: 10.3389/fbioe.2021.764193

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