Article
Enhancing chondrogenic phenotype for cartilage tissue engineering: monoculture and coculture of articular chondrocytes and mesenchymal stem cells.
Tissue engineering. Part B, Reviews - 1 Dec 2014
Hubka Kelsea M, Dahlin Rebecca L, Meretoja Ville V, Kasper F Kurtis, Mikos Antonios G
Abstract excerpt
Articular cartilage exhibits an inherently low rate of regeneration. Consequently, damage to articular cartilage often requires surgical intervention. However, existing treatments generally result in the formation of fibrocartilage tissue, which is inferior to native articular cartilage. As a result, cartilage engineering strategies seek to repair or replace damaged cartilage with an engineered tissue that...
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