Article
Type II restriction endonuclease R.Eco29kI is a member of the GIY-YIG nuclease superfamily.
BMC structural biology - 12 Jul 2007
Ibryashkina Elena M, Zakharova Marina V, Baskunov Vladimir B, Bogdanova Ekaterina S, Nagornykh Maxim O, Den'mukhamedov Marat M, Melnik Bogdan S, Kolinski Andrzej, Gront Dominik, Feder Marcin, Solonin Alexander S, Bujnicki Janusz M
Abstract excerpt
BACKGROUND: The majority of experimentally determined crystal structures of Type II restriction endonucleases (REases) exhibit a common PD-(D/E)XK fold. Crystal structures have been also determined for single representatives of two other folds: PLD (R.BfiI) and half-pipe (R.PabI), and bioinformatics analyses supported by mutagenesis suggested that some REases belong to the HNH fold. Our previous bioinformatic...
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