Article
Structural assessment of glycyl mutations in invariantly conserved motifs.
Proteins - 15 Nov 2007
Prakash Tulika, Sandhu Kuljeet Singh, Singh Nitin Kumar, Bhasin Yasha, Ramakrishnan C, Brahmachari Samir K
Abstract excerpt
Motifs that are evolutionarily conserved in proteins are crucial to their structure and function. In one of our earlier studies, we demonstrated that the conserved motifs occurring invariantly across several organisms could act as structural determinants of the proteins. We observed the abundance of glycyl residues in these invariantly conserved motifs. The role of glycyl residues in highly conserved motifs has...
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