Article

Compositional restrictions in the flanking regions give potential specificity and strength boost to binding in short linear motifs

2024-05-14

Abstract excerpt

Short linear motif (SLiM)-mediated protein–protein interactions play important roles in several biological processes where transient binding is needed. They usually reside in intrinsically disordered regions (IDRs), which makes them accessible for interaction. Although information about the possible necessity of the flanking regions surrounding the motifs is increasingly available, it is still unclear if there are...

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Literature Corpus work: b8b3be4a-d361-5601-8b37-1255b17319ee
DOI: 10.1101/2024.05.13.593809

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