Article
Structure-based comparative analysis and prediction of N-linked glycosylation sites in evolutionarily distant eukaryotes.
Genomics, proteomics & bioinformatics - 1 Apr 2013
Lam Phuc Vinh Nguyen, Goldman Radoslav, Karagiannis Konstantinos, Narsule Tejas, Simonyan Vahan, Soika Valerii, Mazumder Raja
Abstract excerpt
The asparagine-X-serine/threonine (NXS/T) motif, where X is any amino acid except proline, is the consensus motif for N-linked glycosylation. Significant numbers of high-resolution crystal structures of glycosylated proteins allow us to carry out structural analysis of the N-linked glycosylation sites (NGS). Our analysis shows that there is enough structural information from diverse glycoproteins to allow the...
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