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Article

Sets of covariant residues modulate the activity and thermal stability of GH1 β-glucosidases.

PloS one - 1 Jan 2014

Tamaki Fábio K, Textor Larissa C, Polikarpov Igor, Marana Sandro R

Abstract excerpt

The statistical coupling analysis of 768 β-glucosidases from the GH1 family revealed 23 positions in which the amino acid frequencies are coupled. The roles of these covariant positions in terms of the properties of β-glucosidases were investigated by alanine-screening mutagenesis using the fall...

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PMID: 24804841
DOI: 10.1371/journal.pone.0096627
PMCID: PMC4013033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24804841-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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