Article
The genetic complexity of common cancers and the promise of personalized medicine: is there any hope?
The Journal of pathology - 1 Jan 2014
Arnedos Monica, Vielh Philippe, Soria Jean-Charles, Andre Fabrice
Abstract excerpt
Molecular characterization of frequent cancers has shown that these entities actually include a very large number of rare genomic diseases. The progression of each of these rare diseases is being driven by specific genomic alterations, leading to abnormal proteins that can be targeted. Based on this observation, several personalized medicine programmes have been launched. They consist in profiling the tumour...
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