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Expression profiling reveals genes associated with transendothelial migration of tumor cells: A functional role for αvβ3 integrin

9 Jul 2007

Abstract excerpt

Transendothelial migration is a key step in the extravasation of tumor cells during metastasis formation. Here, we have classified 45 human tumor cell lines derived from various tissues according to their capacity for transendothelial migration in vitro. We could distinguish cell lines showing strong transmigration (TEM+ cell lines) from others that did not transmigrate (TEM- cell lines). By DNA microarray...

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PMID: 17621633
DOI: 10.1002/ijc.22879

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