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Article

A robust in vitro model for trans-lymphatic endothelial migration.

Scientific reports - 9 May 2017

Xiong Yanbao, Brinkman C Colin, Famulski Konrad S, Mongodin Emmanuel F, Lord Colin J, Hippen Keli L, Blazar Bruce R, Bromberg Jonathan S

Abstract excerpt

Trans-endothelial migration (TEM) is essential for leukocyte circulation. While much is known about trans-blood endothelial migration, far less is known about trans-lymphatic endothelial migration. We established an in vitro system to evaluate lymphatic TEM for various cell types across primary mouse and human lymphatic endothelial cells (LEC), and validated the model for the murine LEC cell line SVEC4-10. T...

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Identifiers

PMID: 28487567
DOI: 10.1038/s41598-017-01575-w
PMCID: PMC5431648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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