Article
The "chemoinvasion assay": a tool to study tumor and endothelial cell invasion of basement membranes.
The International journal of developmental biology - 1 Jan 2004
Albini Adriana, Benelli Roberto, Noonan Douglas M, Brigati Claudio
Abstract excerpt
Several genetic and epigenetic factors, both in the cell and in the host, contribute to the progression of tumors towards metastases. The escape of cancer cells from a primary, localized tumor to distant organs transforms a relatively curable pathology to an almost untreatable one. Metastatic lesions are often resistant to cancer therapy because of the progressive phenotypic changes that they have undergone. In...
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