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Article

Correlation of Daptomycin Resistance in a Clinical <i>Staphylococcus aureus</i> Strain with Increased Cell Wall Teichoic Acid Production and <scp>d</scp> -Alanylation

24 May 2011

Abstract excerpt

Cell wall thickening is a common feature among daptomycin-resistant Staphylococcus aureus strains. However, the mechanism(s) leading to this phenotype is unknown. We examined a number of cell wall synthesis pathway parameters in an isogenic strain set of S. aureus bloodstream isolates obtained from a patient with recalcitrant endocarditis who failed daptomycin therapy, including the initial daptomycin-susceptible...

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PMID: 21606222
DOI: 10.1128/aac.01226-10

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