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Article

An association of Hutchinson-Gilford progeria and malignancy.

American journal of medical genetics. Part A - 15 Aug 2007

Shalev Stavit A, De Sandre-Giovannoli Annachiara, Shani Ayelet Adir, Levy Nicolas

Abstract excerpt

Mutations in the LMNA gene encoding lamins A/C are responsible for a variety of disorders, commonly referred to as "laminopathies," including the segmental premature aging syndrome Hutchinson-Gilford progeria. We describe in this report the rare association of osteosarcoma and slowly progressing progeria in an 11-year-old girl carrying a truncating heterozygous c.1868C > G (p.T623S) prelamin A mutation. These...

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Source

Identifiers

PMID: 17618517
DOI: 10.1002/ajmg.a.31803

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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