Article
More evidence supports the association of PPP3CC with schizophrenia.
Molecular psychiatry - 1 Oct 2007
Liu Y L, Fann C S J, Liu C M, Chang C C, Yang W C, Hung S I, Yu S L, Hwang T J, Hsieh M H, Liu C C, Tsuang M M, Wu J Y, Jou Y S, Faraone S V, Tsuang M T, Chen W J, Hwu H-G
Abstract excerpt
Calcineurin is a calcium/calmodulin-dependent protein phosphatase composed of two subunits, a regulatory subunit of calcineurin B (CNB) and a catalytic subunit of calcineurin A (CNA). PPP3CC is the gamma isoform of CNA located at the chromosome 8p21.3 region. To evaluate the association between PPP3CC and schizophrenia in the Taiwanese population, 10 single nucleotide polymorphism (SNP) markers across the gene...
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