Article
Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
McKnight Amy-Jayne, Maxwell A Peter, Patterson Chris C, Brady Hugh R, Savage David A
Abstract excerpt
Vascular endothelial growth factor (VEGF) is reported to be implicated in the development of diabetic nephropathy. We performed a case-control study to determine if VEGF-2578C-->A, VEGF-1499C-->T, and VEGF-635G-->C single-nucleotide polymorphisms (SNPs) in the VEGF gene are associated with predisposition to diabetic nephropathy in type 1 diabetes. Genomic DNA was obtained from Irish type 1 diabetic individuals...
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