Article
Functional vascular endothelial growth factor -634G>C SNP is associated with proliferative diabetic retinopathy: a case-control study in a Brazilian population of European ancestry.
Diabetes care - 1 Feb 2007
Errera Flavia I V, Canani Luís Henrique, Silva Maria Elisabeth R, Yeh Erika, Takahashi Walter, Santos Katia G, Souto Katia E P, Tschiedel Balduíno, Roisenberg Israel, Gross Jorge Luis, Passos-Bueno Maria Rita
Abstract excerpt
OBJECTIVE: The purpose of this study was to evaluate the effect of the single nucleotide polymorphism (SNP) -634G>C at the 5' regulatory region of the vascular endothelial growth factor (VEGF) in the risk of proliferative diabetic retinopathy (PDR) in the Brazilian population of European ancestry with type 2 diabetes. RESEARCH DESIGN AND METHODS: A case-control study was conducted in 501 type 2 diabetic patients...
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