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Article

Association Between the ANGPT2 rs2442598 Polymorphism and Diabetic Nephropathy in Slovenian Patients with Type 2 Diabetes Mellitus.

Genes - 25 Mar 2026

Nussdorfer Petra, Letonja Jernej, Završnik Matej, Matos Boštjan, Petrovič Danijel, Cilenšek Ines

Abstract excerpt

Background: The aim of our study was to evaluate the association of angiopoietin 2 (ANGPT2) rs2442598 and vascular endothelial growth factor A (VEGFA) rs2010963 with diabetic nephropathy (DN) in Slovenian subjects with type 2 diabetes mellitus (T2DM). Angiopoietin-endothelial tyrosine kinase receptor (Ang-Tie2) and VEGF-A signaling regulate glomerular endothelial stability and permeability and may contribute to...

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Source

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Identifiers

PMID: 42074491
DOI: 10.3390/genes17040373
PMCID: PMC13116759

Genes

ANGPT2
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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