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Article

Common genetic variants in dyslipidemia, inflammation, and angiogenesis pathways associated with diabetic nephropathy in Tunisians.

Endocrine - 10 Aug 2026

Moussa Amira, Methnani Jabeur, Hassine Refka, Abbes Houwaida, Ammar Mariem, Bjaoui Wided, Triki Sonia, Koubaa Afifa, Amor Dorra, Rejeb Nabila Ben, Neffati Fadoua, Najjar Med-Fadhel, Bouslama Ali, Omezzine Asma

Abstract excerpt

INTRODUCTION: Dyslipidemia, inflammation and angiogenesis pathways contribute to the genetic susceptibility to diabetic nephropathy (DN) in type 2 diabetes mellitus (T2DM). This study investigated the association of common genetic variants; Apolipoprotein C1 (APOC1) rs4420638, C-C chemokine receptor type 5 (CCR5) rs1799987, C-X-C motif chemokine ligand 8 (CXCL8) rs4073, Matrix metallopeptidase 9 (MMP9) rs17576,...

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Topics

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Share to Aged
Share to Diabetes Mellitus, Type 2
Share to Diabetic Nephropathies
Share to Dyslipidemias
Share to Gene Frequency
Share to Inflammation
Share to Neovascularization, Pathologic
Share to Tunisia

Source

Identifiers

PMID: 42573890
DOI: 10.1007/s12020-026-04750-0

Genes

APOC1
CXCL8
CCR5
EPO
MMP9
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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