Article
Expression evolution in yeast genes of single-input modules is mainly due to changes in trans-acting factors.
Genome research - 1 Aug 2007
Wang Daryi, Sung Huang-Mo, Wang Tzi-Yuan, Huang Chih-Jen, Yang Peggy, Chang Tiffany, Wang Yang-Chao, Tseng Da-Lun, Wu Jen-Pey, Lee Tso-Ching, Shih Ming-Che, Li Wen-Hsiung
Abstract excerpt
Both cis- and trans-regulatory mutations contribute to gene expression divergence within and between species. To estimate their relative contributions, we examined two yeast strains, BY (a laboratory strain) and RM (a wild strain), for their gene-expression divergence by microarray. Using these data and published ChIP-chip data, we obtained a set of single-regulator-regulated genes that showed expression...
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