Article
Roles of trans and cis variation in yeast intraspecies evolution of gene expression.
Molecular biology and evolution - 1 Nov 2009
Sung Huang-Mo, Wang Tzi-Yuan, Wang Daryi, Huang Yu-Shan, Wu Jen-Pey, Tsai Huai-Kuang, Tzeng Jengnan, Huang Chih-Jen, Lee Yi-Chen, Yang Peggy, Hsu Joyce, Chang Tiffany, Cho Chung-Yi, Weng Li-Chuan, Lee Tso-Ching, Chang Tien-Hsien, Li Wen-Hsiung, Shih Ming-Che
Abstract excerpt
Both cis and trans mutations contribute to gene expression divergence within and between species. We used Saccharomyces cerevisiae as a model organism to estimate the relative contributions of cis and trans variations to the expression divergence between a laboratory (BY) and a wild (RM) strain of yeast. We examined whether genes regulated by a single transcription factor (TF; single input module, SIM genes) or...
Topics
- Evolution, Molecular
- Gene Expression Regulation, Fungal
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Analysis, DNA