Article
TGFBR1*6A polymorphism in sporadic and familial colorectal Carcinoma: a case-control study and systematic literature review.
Journal of gastrointestinal cancer - 1 Dec 2014
Ibrahim Tony, Yazbeck Charbel, Maalouly Georges, Baz Maria, Haddad Fady, Sabbagh Chadi, Chahine Georges
Abstract excerpt
BACKGROUND: The role of genetic factors in colorectal cancer pathogenesis is widely accepted. Polymorphisms are actually thought to play a role in the unexplained colorectal cancer (CRC) susceptibility. There is conflicting data regarding the role of the transforming growth factor beta receptor 1 polymorphism 6A (TGFBR1*6A) in the increased incidence of CRC. PURPOSE: Our aim is to test the association between...
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