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Article

Deletion of the high-affinity cAMP phosphodiesterase encoded by PDE2 affects stress responses and virulence in Candida albicans.

Molecular microbiology - 1 Aug 2007

Wilson Duncan, Tutulan-Cunita Andreea, Jung WonHee, Hauser Nicole C, Hernandez Rosa, Williamson Tom, Piekarska Katarzyna, Rupp Steffen, Young Tim, Stateva Lubomira

Abstract excerpt

Previously, we have shown that PDE2 is required for hyphal development and cell wall integrity in Candida albicans. In the present study, we have investigated the effects of its deletion by genome-wide transcriptome profiling. Changes in expression levels of genes involved in metabolism, transcription, protein and nucleic acids synthesis, as well as stress responses, cell wall and membrane biogenesis, adherence...

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Share to 3',5'-Cyclic-AMP Phosphodiesterases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Fungal

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Share to Phosphoric Diester Hydrolases

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Source

Identifiers

PMID: 17614954
DOI: 10.1111/j.1365-2958.2007.05788.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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