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Article

Multiple roles and diverse regulation of the Ras/cAMP/protein kinase A pathway in Candida albicans

9 Oct 2018

Abstract excerpt

Candida albicans is a major fungal pathogen of humans, causing both superficial and life-threatening systemic infections in immunocompromised people. The conserved Ras/cAMP/PKA pathway plays a key role in regulating multiple traits important for the virulence of C. albicans such as cell growth, yeast-hyphal transition, white-opaque switching, sexual reproduction and biofilm development. Diverse external signals...

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PMID: 30299574
DOI: 10.1111/mmi.14148

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