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Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in <i>Candida albicans</i>

2021-03-08

Abstract excerpt

<h4>ABSTRACT</h4> Microbial pathogens grow in a wide range of different morphologies that provide distinct advantages for virulence. In the fungal pathogen Candida albicans , adenylyl cyclase (Cyr1) is thought to be a master regulator of the switch to invasive hyphal morphogenesis and biofilm formation. However, faster growing cyr1 Δ/Δ pseudorevertant (PR) mutants were identified that form hyphae in the absence...

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Literature Corpus work
b1dc73b0-15ba-5cc1-a352-24a82fb3728a
DOI
10.1101/2021.03.08.433668
Open publication

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Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in <i>Candida albicans</i>DOI 10.1101/2021.03.08.433668
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