Article
Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff.
Human mutation - 1 Nov 2007
Schoenborn Veit, Gohlke Henning, Heid Iris M, Illig Thomas, Utermann Gerd, Kronenberg Florian
Abstract excerpt
Plasma and serum samples were often the only biological material collected for earlier epidemiological studies. These studies have a huge informative content, especially due to their long follow-up and would be an invaluable treasure for genetic investigations. However, often no banked DNA is available. To use the small amounts of DNA present in plasma, in a first step, we applied magnetic bead technology to...
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