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Comparison of CE- and MPS-based analyses of forensic markers in a single cell after whole genome amplification.

Forensic science international. Genetics - 1 Mar 2020

Chen Man, Zhang Jingjing, Zhao Jing, Chen Tong, Liu Zhiyong, Cheng Feng, Fan Qingwei, Yan Jiangwei

Abstract excerpt

Whole genome amplification (WGA) allows for multiple genetic analyses with low template DNA, such as DNA derived from a single cell. WGA could increase the amount of input DNA from the pg to the μg level. However, there are no studies comparing the performance of forensic markers with DNA from a single cell after WGA evaluated on both capillary electrophoresis (CE) and massively parallel sequencing (MPS)...

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Source

Identifiers

PMID: 31812097
DOI: 10.1016/j.fsigen.2019.102211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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