Article
Genetic epidemiology of low-density lipoprotein subclass phenotypes.
Annals of medicine - 1 Dec 1992
Austin M A
Abstract excerpt
Heterogeneity in LDL particles can be described by two distinct phenotypes in individual subjects, denoted A and B, based on gradient gel electrophoresis. Phenotype A is characterized by a predominance of large, buoyant LDL particles, while phenotype B is characterized by a predominance of small, dense LDL particles. Several studies have demonstrated that LDL subclass phenotype B is associated with both increased...
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