Genetic and environmental influences on LDL subclass phenotypes.

Abstract excerpt

There is accumulating evidence that subclasses of low-density lipoproteins (LDL) are important in atherosclerosis. Several case-control studies have demonstrated that a predominance of small, dense LDL (LDL subclass phenotype B) is associated with increased risk of coronary heart disease (CHD). Phenotype B is also consistently characterized by an atherogenic lipoprotein phenotype, including increased levels of...

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