Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of Fractalkine receptor CX3CR1 and plasma levels of its ligand CX3CL1 in colorectal cancer patients.

International journal of colorectal disease - 1 Oct 2007

Dimberg Jan, Dienus Olaf, Löfgren Sture, Hugander Anders, Wågsäter Dick

Abstract excerpt

BACKGROUND AND AIMS: The chemokine Fractalkine/CX3CL1, which is expressed by epithelial cells within normal colorectal mucosa and in colorectal cancer (CRC), is thought to have a crucial role in colorectal mucosal immunity by recruiting leucocytes via the receptor CX3CR1. The purpose of this study was to investigate two single-nucleotide polymorphisms of the Fractalkine receptor/CX3CR1 gene, V249I and T280M, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Colorectal Neoplasms

Share to CX3C Chemokine Receptor 1

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Receptors, Chemokine

Source

Identifiers

PMID: 17611763
DOI: 10.1007/s00384-007-0343-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of Fractalkine receptor CX3CR1 and plasma levels of its ligand CX3CL1 in colorectal cancer patients.PMID 17611763Read ↗

Fractalkine receptor polymorphism may not be associated with the development and clinical course of ulcerative colitis.Semantic proximity Read ↗

Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype.Semantic proximity Read ↗

Lack of association between the functional CX3CR1 polymorphism V249I and hepatocellular carcinoma.Semantic proximity Read ↗

Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease.Semantic proximity Read ↗

Influence of fractalkine receptor gene polymorphisms V249I-T280M on cancer occurrence after renal transplantation.Semantic proximity Read ↗

Opposite effects of CX3CR1 receptor polymorphisms V249I and T280M on the development of acute coronary syndrome. A possible implication of fractalkine in inflammatory activation.Semantic proximity Read ↗

Polymorphisms of fractalkine receptor CX3CR1 gene in patients with symptomatic and asymptomatic carotid artery stenosis.Semantic proximity Read ↗

Role of the fractalkine receptor CX3CR1 polymorphisms V249I and T280M as risk factors for early-onset coronary artery disease in patients with no classic risk factors.Semantic proximity Read ↗

The fractalkine receptor CX3CR1 is involved in liver fibrosis due to chronic hepatitis C infection.Semantic proximity Read ↗

Polymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patientsSemantic proximity Read ↗

Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine eotaxin-1 in colorectal cancer patients.Semantic proximity Read ↗

Genetic diversity of CX3CR1 gene and coronary artery disease: new insights through a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.