Article
Polymorphisms of fractalkine receptor CX3CR1 gene in patients with symptomatic and asymptomatic carotid artery stenosis.
Journal of atherosclerosis and thrombosis - 1 Oct 2009
Kimouli Maria, Miyakis Spiros, Georgakopoulos Petros, Neofytou Eirini, Achimastos Apostolos D, Spandidos Demetrios A
Abstract excerpt
AIM: The chemokine fractalikine is expressed in vascular endothelium, exerting a pro-atherogenic effect. Two single-nucleotide polymorphisms of the CX3CR1 gene (T280M and V249I) affect frac-talkine receptor expression and function. We aimed to assess the prevalence of CX3CR1 polymor-phisms and the association with ischemic cerebrovascular attacks in a cohort of carotid atheromatous disease patients and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
