Article
Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine eotaxin-1 in colorectal cancer patients.
World journal of surgical oncology - 31 Jul 2007
Wågsäter Dick, Löfgren Sture, Hugander Anders, Dienus Olaf, Dimberg Jan
Abstract excerpt
BACKGROUND: Previous studies suggest that chemokines (chemotactic cytokines) promote and regulate neoplastic progression including metastasis and angiogenesis. The chemokine eotaxin-1 is a powerful eosinophil attractant but also exerts chemotaxis of other leukocytes. Eotaxin-1 has been implicated in gastrointestinal disorders and may play an important role in colorectal mucosal immunity. PATIENTS AND METHODS: The...
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