Article
Lack of association between the functional CX3CR1 polymorphism V249I and hepatocellular carcinoma.
Oncology reports - 1 May 2005
Mühlbauer Marcus, Ringel Susanne, Hartmann Arndt, Lallinger Gertrud, Weiss Thomas S, Gäbele Erwin, Wünsch Peter H, Schölmerich Jürgen, Hellerbrand Claus
Abstract excerpt
Chemokine production by cancer cells constitutes a duality. Leukocyte recruitment under the pressure of chemokines may be beneficial for the host or for the tumor. Recently, the chemokine fractalkine and its receptor CX3CR1 have been shown to be expressed in hepatocytes in vivo and in a human hepatocarcinoma cell line in vitro. Therefore, the aim of this study was to analyze the expression of CX3CR1 in...
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