Article
Gene cluster lock after pheromone receptor gene choice.
The EMBO journal - 25 Jul 2007
Roppolo Daniele, Vollery Sarah, Kan Chen-Da, Lüscher Christian, Broillet Marie-Christine, Rodriguez Ivan
Abstract excerpt
In mammals, perception of pheromones is based on the expression in each vomeronasal sensory neuron of a limited set of receptor genes, chosen among a large repertoire. Here, we report an extremely tight control of the monogenic and monoallelic transcription of the V1rb2 receptor gene. Combining genetic and electrophysiological approaches, we show that the transcription of a non-functional V1r allele leads to the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
