Article
Establishment and maintenance of random monoallelic expression.
Development (Cambridge, England) - 15 May 2024
Kanata Eleni, Duffié Rachel, Schulz Edda G
Abstract excerpt
This Review elucidates the regulatory principles of random monoallelic expression by focusing on two well-studied examples: the X-chromosome inactivation regulator Xist and the olfactory receptor gene family. Although the choice of a single X chromosome or olfactory receptor occurs in different developmental contexts, common gene regulatory principles guide monoallelic expression in both systems. In both cases,...
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