Article
Allelic inactivation regulates olfactory receptor gene expression.
Cell - 9 Sept 1994
Chess A, Simon I, Cedar H, Axel R
Abstract excerpt
We suggest a model in which a hierarchy of controls is exerted on the family of odorant receptor genes to assure that a sensory neuron expresses a single receptor from a family of 1000 genes. We propose that a cis-regulatory element directs the stochastic expression of only one gene from a large array of linked receptor genes. Moreover, only one allelic array encoding multiple receptor genes is active in an...
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