Article
Allelic inactivation regulates olfactory receptor gene expression.
Cell - 9 Sept 1994
Chess A, Simon I, Cedar H, Axel R
Abstract excerpt
We suggest a model in which a hierarchy of controls is exerted on the family of odorant receptor genes to assure that a sensory neuron expresses a single receptor from a family of 1000 genes. We propose that a cis-regulatory element directs the stochastic expression of only one gene from a large...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Replication
- Gene Expression Regulation
- Mice
- Mice, Inbred C57BL
- Models, Genetic
- Molecular Sequence Data
- Multigene Family
- Muridae
- Olfactory Receptor Neurons
- Receptors, Odorant
- Sequence Analysis, DNA
- Sex Factors